About

Kamesh Narasimhan is a seasoned Synthetic Biologist with a rich background in Protein Engineering, Computational Protein Design, Genetic Code Expansion, and Cell-Free Protein Synthesis. He has dedicated his career to bridging the gap between cutting-edge research and practical, real-world applications. His technical skills span a wide range of analytical methods, biophysical techniques, and computational tools, reflecting his holistic approach to scientific problem-solving. In his tenure as a research associate at Harvard Medical School under the mentorship of Professor George Church, Kamesh led multiple high-impact projects and co-wrote grants that secured a total of $32 million in funding from the Department of Energy and the National Science Foundation. His work focused on recoding microbial genomes and incorporating non-canonical amino acids in E.coli. His work has consistently demonstrated a keen ability to transform complex biotech endeavors in the wet-lab into actionable insights through robust and reproducible analysis of experiments workflows. As a Senior Consultant at Dovetail Biopartners, Kamesh leverages his extensive experience to provide strategic guidance for protein and enzyme engineering campaigns. Kamesh offers expertise in computational protein design (both ML and physics based) and in directed evolution based methods in the wet-lab. His deep understanding of the protein engineering space, genetic code expansion technology, and computational protein design ensures a pragmatic and solutions-oriented approach for projects of varying complexity, budgets, resources and timelines.