Daniel Dacey

Tome Biosciences: What Went Wrong and How to Avoid Their Fate

The Rise and Fall of Tome Biosciences Tome Biosciences launched in December 2023 with an ambitious goal: to revolutionize gene editing through their innovative Programmable Genomic Integration (PGI) platform. Backed by $213 million in Series A and B funding, Tome aimed to precisely insert large DNA sequences into the human genome without causing double-stranded breaks—a …

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Case Study: Developing an MVP for Autoimmune Disease Research Using AI & Imaging Data

We developed a Minimum Viable Product (MVP) for a biotech platform company focused on autoimmune disease therapeutics. Their approach combines high-throughput biological imaging and data analysis to uncover novel therapeutic targets within the immune system. This MVP, leveraging advanced AI and multiplex immunofluorescence technology and Amazon Web Services (AWS), was designed to enhance the client’s …

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Case Study: Enhancing Genomic Data Compression & Analysis for Cancer Research

Client Background A cancer therapeutics company approached us with the need to manage vast amounts of genomic data generated from their research, which was proving to be costly and time-consuming to store and analyze. Our goal was to enhance data compression ratios, accelerate analytical workflows, and ensure robust data security, thereby enabling more efficient research …

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Case Study: Machine Learning Integration for Proteomic Data Analysis in Liver Fibrosis Research

In this case study, we explore our partnership with a biotech firm dedicated to advancing liver fibrosis research. We developed a comprehensive AWS infrastructure that efficiently manages and analyzes high-throughput proteomics data from mass spectrometry. By incorporating machine learning (ML) and artificial intelligence (AI), our solution aimed to identify biomarkers and therapeutic targets, driving significant …

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Understanding Spatial Transcriptomics in Neurobiology

In the field of neurobiology, understanding the complex organization and functioning of the brain is essential for unraveling the mysteries of the human mind. Traditional methods of studying gene expression in the brain, such as RNA sequencing, provide valuable insights into the molecular processes underlying neuronal function. However, these techniques fail to capture the spatial …

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Microbiome Ecological Modelling Overview

The study of the microbiome, the complex community of microorganisms that inhabit our bodies and the environment around us, has gained significant attention in recent years. Understanding the intricate interactions within the microbiome and how it impacts our health and the environment is a fascinating field of research. One powerful tool that scientists have employed …

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Drug Development News – September 11, 2023

In this drug news post, we will be covering a range of innovative products and therapies that are making waves in the field of drug development. From groundbreaking partnerships in cancer research to promising treatments for rare diseases and advancements in targeted therapies, these developments are shaping the future of healthcare. Moderna and Immatics Research …

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The Use of ChIP-seq in Drug Discovery

In recent years, ChIP-seq (Chromatin Immunoprecipitation Sequencing) has emerged as a powerful tool in genomics research, offering valuable insights into the interactions between proteins and DNA. This technique has revolutionized the field of drug discovery, providing researchers with a deeper understanding of the molecular mechanisms underlying diseases and aiding in the identification of potential drug …

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